Coronary artery disease
Conditions
Interventions
case series:Nil
Sponsors
Shanghai Chest Hospital, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Male or female aged >= 18 years; 2. Diagnosed as NSTE-ACS with at least two of the following:symptoms of myocardial ischemia;abnormal ST segment (depression or transient elevation >= 0.1mv) or T wave inversion on the ECG (>= 2 relevant leads); elevated cTn; 3. Patients with intermediate or high risk: complicated with diabetes, renal insufficiency (eGFR 109; 4. Plan to undergo PCI (intervention time point according to the doctor's judgment), and plan to use aspirin and a P2Y12 receptor inhibitor for at least one year after surgery; 5. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Female patients who are breastfeeding or who may be pregnant; 2. Patients with stable coronary heart disease; 3. Interventional surgery should be performed more than 96 hours after symptoms appear; 4. STEMI patients or STEMI before intervention; 5. The patient plans to undergo CABG; 6. The patient is unable or refuses to undergo PCI; 7. The patient has bleeding tendency, active bleeding, coagulation dysfunction or blood system disease; 8. The patient has been taking any P2Y12 receptor inhibitor for a long time; 9. The patient takes anticoagulation therapy for a long time; 10. The patient has used any thrombolytic therapy since the onset of the disease; 11. The patient has contraindications to taking aspirin or P2Y12 receptor inhibitors; 12. The patient has malignant tumor and/or life expectancy is less than 1 year; 13. During the study period, the patient wishes to discontinue participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet function;Myocardial perfusion; | — |
Countries
China
Contacts
Public ContactShen Linghong
Shanghai Chest Hospital
Outcome results
None listed