End-stage renal disease
Conditions
Interventions
Gold Standard:Serum creatinine, glomerular filtration rate, ultrasound and renal graft biopsy were used to determine graft function, survival and rejection.
Index test:Mitochondrial DNA
Sponsors
The Third Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
Male
Age
16 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Recipients aged 16 to 70 years; 2. Indications for kidney transplantation; 3. DBD donor kidney was used for transplantation; 4. First kidney transplantation; 5. BPAR, no contraindications for biopsy; 6. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Donors with multiple organ injuries 2. Patients with absolute contraindications for kidney transplantation; 3. Drug combination within the specified scope, especially drugs which have a great influence on the test results, and affect the judgment of efficacy and safety; 4. Participants in other clinical trials; 5. Previous history of organ transplantation; 6. Other circumstances that the researcher considers unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mitochondrial DNA;Accuracy, specificity, sensitivity, AUC of ROC; | — |
Countries
China
Contacts
Public ContactHan Fei
The Third Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed