Presbycusis, cognitive dysfunction
Conditions
Interventions
experimental group:with hearing-aid
control group:none
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria for the experimental group: This experiment included binaural sensorineural hearing loss aged 55 years and above (according to the World Health Organization standard, 0.5,1,2,4kHz average value > 25dBHL), if the degree of binaural hearing loss is different, better The degree of ear hearing loss shall prevail). With the naked eye or wearing glasses, you can clearly see fonts of the same size as the Digit Symbol Substition Test (DSST) test. There was no cognitive decline in the DSST test. The hand can hold a pen and write. According to the degree of hearing loss, both ears are fitted with hearing aids suitable for the degree of hearing loss. Inclusion criteria for the control group: binaural sensorineural hearing loss aged 55 years and above (according to the World Health Organization standard, 0.5,1,2,4kHz average value > 25dBHL), if the degree of binaural hearing loss is different, better The degree of ear hearing loss shall prevail). With the naked eye or wearing glasses, you can see fonts of the same size as the DSST test. There was no cognitive decline in the DSST test. The hand can hold a pen and write. He is not wearing a hearing device.
Exclusion criteria
Exclusion criteria: Carrying 3 pathogenic genes of dementia (amyloid precursor gene (APP) of chromosome 21, PSEN1 of chromosome 14 presenilin-1 gene, PSEN2 of chromosome 1 presenilin-2 gene), first-degree relatives (parents, brothers) Sisters) have hospitals diagnosed patients with dementia, MRI showed cerebral hemorrhage, cerebral infarction, cerebrovascular disease, or previous hospitals diagnosed cerebral hemorrhage, cerebral infarction or cerebrovascular disease, abnormal blood pressure (according to the 2019 Chinese Medical Association promulgation Guidelines for the primary diagnosis and treatment of hypertension, hypertension systolic blood pressure >= 140mmHg and/or diastolic blood pressure >= 90mmHg), abnormal blood glucose (according to the position statement issued by the Australian Diabetes Association in 2015, using glycosylated hemoglobin (HbA1c) as a diagnosis of type 2 diabetes is cost-effective and effective , Simple diagnostic tools, HbA1c>6.5% is the diagnostic criteria), abnormal body mass (according to the Body Mass Index (BMI) Chinese reference standard, weight/height 2>24 overweight, BMI= 11 lungs (Moderately affected functions), syphilis, HIV, living alone without social activities, pure tone audiometry is neurological hearing loss, and posterior cochlear hearing loss with normal otoacoustic emission. Binaural or monaural hearing loss is conductive or mixed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Digit Symbol Substitution Test;Mini-Mental State Examination;pure-tone auditory; | — |
Countries
China
Contacts
Public ContactZhaoli Meng
Outcome results
None listed