Gestational diabetes mellitus
Conditions
Interventions
Experimental group:supplement of vitamin D3 with 2400 IU per day
Sponsors
Anhui Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Pregnant women with insufficient vitamin D (25-OHD<75nmol/L) and diagnosed with GDM at 24-28 weeks of gestation at the first investigation; 2. Live in the urban area of Hefei during pregnancy, and plan to have an obstetric examination and give birth at the research site; 3. Singleton pregnancy; 4. Aged 18 to 40 years; 5. Voluntarily participate in regular follow-up after being informed; 6. Can clearly answer the questions of the questionnaire.
Exclusion criteria
Exclusion criteria: 1. Adopt assisted reproductive technology; 2. Suffering from severe organic disease or mental disease; 3. Serious complications during pregnancy; 4. Long-term use of drugs that affect liver and kidney function; 5. Those who do not cooperate with completing the questionnaire.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| level of serum 25(OH)D;Maternal and umbilical cord blood glucose and lipid;Birth outcomes;Non-targeted metabolomics Maternal and umbilical cord blood in;Neurodevelopment screen in 6-24 mo of infants;Neurodevelopmental diagnosis (autism and attention deficit hyperactivity disorder) and intelligence assessment for children 3-6 years old;Imaging examination of brain function in children aged 5-7; | — |
Countries
China
Contacts
Public ContactZhu Peng
Anhui Medical University
Outcome results
None listed