Postoperative cognitive function
Conditions
Interventions
Intravenous anesthesia group:Propofol was administered to maintain anesthesia during surgery
Inhalational anesthesia group:Inhaled anaesthetics (sevoflurane or desflurane) was administered during surgery
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Residents in Chengdu, aged >= 65 years; 2. Elective non cardiac, non neurosurgical elective surgery; 3. Patients with an anticipated anesthesia time over 2 hours.
Exclusion criteria
Exclusion criteria: 1. History of schizophrenia, epilepsy, Parkinson and so on; 2. Inability to communicate due to coma, severe dementia, speech impairment or critical illness; 3. ASA grade > III; 4. Previous history of malignant hyperthermia or propofol infusion syndrome; 5. Participated in other clinical trials 3 months prior to study enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of delayed neurocognitive recovery (DNR); | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of delirium ;Severity of postoperative delirium;Quality of life score ;Pain scores;Postoperative complications;Hospital stay;Hospitalization expenses; | — |
Countries
China
Contacts
Public ContactYang Jing
West China Hospital
Outcome results
None listed