Mild cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: aMCI patients: 1. Meet the diagnostic criteria of mild cognitive impairment; 2. Aged 50-80 years, unlimited gender, right-handed; 3. The complaint was memory loss with objective evidence (neuropsychological scale evaluation); 4. Years of education >= 6 years; 5. Those who understand and agree to participate in this study signed the informed consent form. Healthy subjects: 1. No chief complaint of cognitive impairment; 2. Aged 50-80 years, unlimited gender, right-handed; 3. No cognitive impairment (assessed by neuropsychological scale); 4. Years of education >= 6 years; 5. Those who understand and agree to participate in this study signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Complicated with tumor, severe heart, liver, kidney, blood system diseases or infectious diseases; 2. Previous neurological diseases such as cerebrovascular disease, Parkinson's syndrome and dementia caused by various reasons; 3. Previous mental diseases such as anxiety, depression and schizophrenia; 4. Severe audiovisual impairment; 5. There are magnetic resonance contraindications (such as a cardiac pacemaker, a cardiac stent, artificial heart valve, fixed plate after fracture surgery, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuropsychological test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Magnetic Resonance Imaging;Neuroelectrophysiological indexes;Emotional and daily living ability test;TCM Syndrome Scale; | — |
Countries
China
Contacts
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine