Acute ischemic stroke
Conditions
Interventions
Acute balloon angioplasty group:No
Acute stenting group:No
Sponsors
Jiangsu Province Hospital (The First Affiliated Hospital of Nanjing Medical University)
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. >= 18 years old; 2. CTA confirmed responsible internal carotid artery or middle cerebral artery M1 segment (TICI grade 0-1); 3. For stroke patients with awakening stroke or stroke onset at 6-24 hours, RAPID imaging results must meet the criteria of DAWN or DEFFUSE3 before endovascular treatment; 4. Baseline ASPECTS score >= 6; 5. Baseline NIHSS score >= 6; 6. Pre-stroke mRS 50% was confirmed during the procedure.
Exclusion criteria
Exclusion criteria: 1. Hemorrhagic physique, coagulation factor deficiency or oral anticoagulant therapy (INR > 3.0); 2. Baseline platelet count 400mg/dL; 4. Intractable hypertension uncontrolled by drugs (systolic blood pressure > 220 mmHg, or diastolic blood pressure > 110 mmHg); 5. End-stage diseases leading to patients' expected survival time of less than one year; 6. Patients with severe allergy to contrast media; 7. Patients with renal insufficiency (serum creatinine >= 3 mg/dL); 8. Pregnant or lactating female patients; 9. Patients with neurological or mental disorders before onset; 10. Patients who could not complete 90-day follow-up (such as no fixed residence, overseas patients, etc.); 11. Imaging: (1) The ASPECTS score of anterior circulation on baseline CT scan was less than 6; (2) CT indicated intracranial hemorrhage; (3) CTA showed vascular occlusion in both anterior and posterior circulation; (4) Patients with intracranial tumors (except small meningiomas).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical outcome at 3 months;Stroke recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vascular recanalization;Proportion of patients with good early response after treatment;Quality of life assessment; | — |
Countries
China
Contacts
Public ContactShi Haibin
Jiangsu Province Hospital (The First Affiliated Hospital of Nanjing Medical University)
Outcome results
None listed