Infertility with Overweight Polycystic Ovary Syndrome
Conditions
Interventions
Experimental group:Western Medicine and Modified Cangfu Daotan Granule
Control group:Western Medicine and placebo granule
Sponsors
Maternal and Child Health Hospital of Hubei Province
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria of overweight, PCOS and infertility, as well as the TCM syndrome differentiation criteria of kidney deficiency and phlegm dampness syndrome; 2. Female aged 20-40 years; 3. Willing to receive treatment and voluntarily sign informed consent; 4. There were no organic lesions in the reproductive system; 5. Bilateral fallopian tubes were unobstructed by radiography; 6. Immune infertility antibodies were normal.
Exclusion criteria
Exclusion criteria: 1. Complicated with serious primary diseases such as cardiovascular, liver, kidney and hematopoietic system; 2. High gonadotropins such as premature ovarian failure and ovarian insensitivity syndrome; 3. Adrenal glands, thyroid, diabetes and other endocrine glands were abnormal; 4. Male infertility factors; 5. Psychiatric patients; 6. Allergic constitution or allergic to the study drug; 7. Patients with metformin contraindications; 8. Patients with contraindications or cautious use of short acting compound oral contraceptives (COC); 9. Failure to use drugs according to regulations, inability to judge the curative effect or incomplete data affect the judgment of curative effect.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Continuous pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body mass index;TCM syndrome score;Sex hormone;Homeostatic model assessment of insulin resistance;Effective rate;Cure rate;Cycle ovulation rate;Pregnancy rate;Clinical pregnancy rate;Early pregnancy loss rate; | — |
Countries
China
Contacts
Public ContactHe Danjuan
Maternal and Child Health Hospital of Hubei Province
Outcome results
None listed