Adult Philadelphia-negative Acute Lymphoblastic Leukemia
Conditions
Interventions
pediatric-regimen group:Nil
adult-regimen group:Nil
Sponsors
Nanfang Hospital of Nanfang Medical University
Eligibility
Sex/Gender
All
Age
14 Years to 60 Years
Inclusion criteria
Inclusion criteria: The subjects must meet the following criteria to be eligible for study entry: 1.Aged 14-60 years; 2.Newly diagnosed Ph-negative B-ALL; 3.Eligible for allo-HSCT; 4.The functions of vital organs meet the following requirements: LVEF >= 50%; TBIL <= 1.5ULN; AST/ALT <= 2.5ULN; Serum creatinine <= 1.5ULN. 5.Researchers assess expected lifetime is more than 3 months; 6.Informed consent was obtained.
Exclusion criteria
Exclusion criteria: 1.Burkitt lymphoma/leukemia; 2.T-cell precursor acute lymphoblastic lymphoma/leukemia; 3.Acute undifferentiated leukemia; 4.Being pregnant; 5.Severe active infection; 6.History of gastrointestinal bleeding during the past 6 months; 7.History of artery/vein thrombosis during the past 6 months; 8.Other active malignancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| leukemia free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival; | — |
Countries
China
Contacts
Public ContactLiu Qifa
Nanfang Hospital affiliated to Southern Medical University
Outcome results
None listed