Gastrointestinal dysfunction
Conditions
Interventions
control group:Induction with 2.0 mg / kg propofol
experimental group:Induction with 0.4mg / kg ciprofol
Sponsors
Liaoning Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients who need colonoscopy for gastrointestinal diseases; 2. Aged 18-70 years, no gender limit, ASA I-II grade; 3. Obtain the informed consent of the patient or his guardian.
Exclusion criteria
Exclusion criteria: 1. BMI > 30kg/m^2; 2. History of allergy to propofol, soy, egg or opioids; 3. Known or predicted airway difficulty (such as Mallampati grade 3 or 4); 4. Severe hypertension (the control of hypertension is still above grade III after taking medicine), cardiac insufficiency (LVEF: 1.5 times the upper limit of normal or GFR < 40ml/min); 7. History of taking sedatives, antidepressants, alcoholism and drug addiction; 8. Patients who are unable to understand the research protocol, difficult to communicate in language, and uncooperative; 9. Pregnant and lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnosis and treatment operation;Gender;Age;Height;Weight;Body mass index;ASA classification;Systolic pressure;Diastolic pressure;Mean arterial pressure;Heart rate;Oxygen saturation;Dosage of ciprofol/propofol;Additional ciprofol / propofol dose;Administration time;Lowest oxygen saturation;Lowest heart rate;Lowest mean arterial pressure;Onset time;Operation time;Recovery time;Room departure time;Injection pain;Choking cough;Muscle fasciculation;Hypoxemia;Apnea;Airway obstruction;Hypotension;Tachycardia;Bradycardia;Nausea;Vomit;Drowsiness;Vertigo;Postoperative pain score;Patient satisfaction;Surgeon satisfaction;Intraoperative awareness; | — |
Countries
China
Contacts
Public ContactGao Shihui
Liaoning Provincial People's Hospital
Outcome results
None listed