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Clinical study on the effect of edaravone and dexbornol on the levels of inflammatory factors in patients with massive cerebral infarction

Clinical study on the effect of edaravone and dexbornol on the levels of inflammatory factors in patients with massive cerebral infarction

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053196
Enrollment
Unknown
Registered
2021-11-14
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

massive cerebral infarction

Interventions

control group :Routine treatment of cerebral infarction (anti-platelet, regulating blood lipid, improving circulation, etc.)
experimental group:Adequate dosage and course of Dexborneol Concentrated Solution for Injection were used during hospitalization

Sponsors

Longyan First Hospital Affiliated to Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with new cerebral infarction who were hospitalized in our hospital and admitted to the hospital within 48 hours of onset; 2. Aged between 18-80 years; 3. Patients with cerebral infarction who have been diagnosed with cerebral infarction by head CT or MRI and meet the diagnostic criteria for large-area cerebral infarction (The diagnostic criteria for large-area cerebral infarction: the infarction of the cerebral hemisphere exceeds one lobe, and the diameter of the infarction measured by cranial CT or MRI is greater than 5 cm).

Exclusion criteria

Exclusion criteria: 1. Combined with severe organ failure (heart, liver and kidney failure); 2. Patients with severe respiratory infection and other organ infections; 3. Patients with moderate or higher anemia or coagulation dysfunction or other serious blood system diseases; 4. Patients with severe endocrine diseases; 5. Patients with autoimmune system diseases; 6. Patients with malignant tumor; 7. Patients or their guardians are unwilling to participate in the project.

Design outcomes

Primary

MeasureTime frame
IL1-ß;IL-4;IL-6;TNF-a;Hypersensitive C-reactive protein;

Countries

China

Contacts

Public ContactHu Xiaohong

Longyan First Hospital Affiliated to Fujian Medical University

hxh19790601@sina.com+86 13850685180

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026