cervical human papillomavirus infection and cervical intraepithelial neoplasia I
Conditions
Interventions
Experimental group:Dingjunsheng for vagina
Control group:Vaginal placebo
Sponsors
Chinese Academy of Medical Sciences and Peking Union Medical College Peking Union Medical College Hospital
Eligibility
Sex/Gender
Female
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 25-65 years; 2. TCT: ASCUS, LSIL, HPV16/18 positive or HPV other 12 positive (1 year interval), colposcopy biopsy diagnosed as CIN I or TCT: ASCUS, LSIL or normal, HPV16/18/other12 positive, no CIN I on colposcopy biopsy.
Exclusion criteria
Exclusion criteria: 1. TCT: ASC-H or HSIL or glandular epithelial lesions; 2. History of cervical surgery; 3. Pregnancy or breastfeeding; 4. Autoimmune diseases or immunodeficiency diseases (SLE, SS, AIDS, etc.); 5. Long-term use of immunosuppressive drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cervical cytology(TCT);human papillomavirus infection; | — |
Secondary
| Measure | Time frame |
|---|---|
| vaginal microbiota; | — |
Countries
China
Contacts
Public ContactZhu Lan
Beijing Union Medical College Hospital
Outcome results
None listed