sarcopenia
Conditions
Interventions
Control group:Oral vitamin D
Iron-lowering drug intervention group:Oral vitamin D and deferasirox
Sponsors
Affiliated Hospital of Jiangsu University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 60 years, gender is not limited; 2. No previous serious systemic medical diseases such as tumors, cardiovascular and cerebrovascular diseases, hyperthyroidism; 3. Meet the aforementioned diagnostic criteria for ''iron accumulation'' sarcopenia; 4. The SF of the patient was higher than the upper limit of normal value before enrollment; 5. Voluntarily accept the treatment and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. There are stress states such as trauma and infection within 3 months before enrollment; 2. Taking drugs that affect muscle and bone function within 6 months before enrollment; 3. Combined with Alzheimer's disease or other types of dementia, disability, mental disorders; 4. Combined with other contraindications that may affect the detection (puncture, MRI, physical fitness).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver iron accumulation index;Serum iron accumulation index;Skeletal muscle mass measurement;Determination of skeletal muscle strength;Activity measurement;Vision;Hearing; | — |
Countries
China
Contacts
Public ContactZhao Guoyang
Affiliated Hospital of Jiangsu University
Outcome results
None listed