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Study on the central analgesic mechanism of moxibustion in the treatment of primary dysmenorrhea based on multimodal functional magnetic resonance imaging

Study on the central analgesic mechanism of moxibustion in the treatment of primary dysmenorrhea based on multimodal functional magnetic resonance imaging

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053181
Enrollment
Unknown
Registered
2021-11-13
Start date
2021-11-18
Completion date
Unknown
Last updated
2022-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Dysmenorrhea

Interventions

Moxibustion group:Moxibustion at RN4 for 30 minutes
Comfort moxibustion group:Comforting moxibustion at RN4 for 30 minutes
Healthy group:None

Sponsors

College of Acupuncture and Tuina, Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Experimental group: (1) Nursing females aged 18-30 years, accept the intervention program of this subject and sign the informed consent. (2) Conform to the western medical diagnostic criteria for primary dysmenorrhea issued by the Canadian Society of Obstetrics and Gynecology in 2005. (3) Conform to the TCM syndrome differentiation type: qi stagnation and blood stasis type, cold-damp stagnation type, or a combination of the above two types. (4) The menstrual cycle is basically normal (28±7) days. (5) The course of disease is more than 6 months. (6) Those who have not taken any medication for dysmenorrhea or other methods of treating dysmenorrhea in the past 1 month. (7) The average score of visual analogue scale (VAS) of pain in the past three menstrual cycles is >=40mm. (8) No brain and nervous system lesions, no contraindications for magnetic resonance examination, and right-handedness. (9) Normal consciousness, cooperative behavior, clear speech, and correct self-reporting of feelings. 2. Healthy group: (1) Nursing females aged 18-30 years, signed the informed consent. (2) The menstrual cycle is basically normal (28±7) days. (3) No history of dysmenorrhea, and no prostaglandin synthase inhibitor in the past 1 month. (4) No brain and nervous system lesions, no contraindications for magnetic resonance examination, and right-handedness. (5) Normal consciousness, cooperative behavior, clear speech, and correct self-reporting of feelings.

Exclusion criteria

Exclusion criteria: 1. Combined with medical history, combined with serious life-threatening primary diseases such as cardiovascular and cerebrovascular, liver, kidney and hematopoietic system, as well as mental patients, asthma patients, etc. 2. Those who need to receive other related treatments that may affect the experimental results of this study. 3. Those who have rich experience in using moxibustion.

Design outcomes

Primary

MeasureTime frame
Functional magnetic resonance imaging;Pain visual analog scale;Anxiety visual analog scale;

Secondary

MeasureTime frame
Infrared thermal imaging;

Countries

China

Contacts

Public ContactHuang Yiran

College of Acupuncture and Tuina, Beijing University of Chinese Medicine

caicai13@126.com+86 13810366537

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026