perioperative pain
Conditions
Interventions
Group 1:Standardized analgesia with flurbiprofen ester
Group 2:Placebo standardized analgesia
Group 3:None
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 65 to 80 years, gender is not limited; 2. ASA IIII grade; 3. Body mass index (BMI) 18-30kg/m^2; 4. General anesthesia surgery, the operation time is 1 to 6 hours; 5. The patients agreed to participate in this study and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Active peptic ulcer disease; 2. Significant abnormalities in the coagulation system and bleeding tendency; 3. Obvious abnormality of liver and kidney function (relevant indicators exceed the upper limit of normal by more than 2 times); 4. Aspirin asthma or allergic to non-steroidal anti-inflammatory drugs; 5. Are using quinolone antibiotics (such as enoxacin, lomefloxacin, norfloxacin, etc.); 6. Patients with heart failure are using furosemide; 7. Hypertension grade III; 8. Patients who are pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Recovery Assessment Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analog Pain Score; | — |
Countries
China
Contacts
Public ContactZheng Xiaochun
Fujian Provincial Hospital
Outcome results
None listed