Clinical application of esketamine-based opioid-reducing anesthesia regimen in gynecological day surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100053153

Enrollment

Unknown

Registered

2021-11-13

Start date

2022-01-01

Completion date

Unknown

Last updated

2022-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Experimental group 1:Replacing opioids with esketamine as an analgesic for maintenance of anesthesia

Experimental group 2:Esketamine as an analgesic instead of opioids in induction and maintenance of anesthesia

Control group:Induction and maintenance of anesthesia with alfentanil as analgesic

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Eligible patients are adult women who plan to undergo gynecological day surgery at Weifang People's Hospital.

Exclusion criteria

Exclusion criteria: 1. Morbid obesity (BMI >30 kg/m^2); 2. Complicated with ischemic heart disease, liver and kidney insufficiency, neuromuscular and mental disorders; 3. History of cerebral infarction, myocardial infarction and severe arrhythmia; 4. Have a history of chronic pain or have taken any sedatives and analgesics; 5. Hypersensitivity to any drug involved in the study.

Design outcomes

Primary

Measure	Time frame
Hemodynamic parameters;Postoperative adverse reaction;Adverse reactions in postanesthesia care unit;	—

Secondary

Measure	Time frame
Drug dosage;Recovery time;	—

Countries

China

Contacts

Public ContactJi Fanceng

Weifang Medical College

jifanceng@163.com+86 13563698838

Outcome results