Epilepsy with cognitive impairment
Conditions
Interventions
Treatment group:Remove blood stasis and settle lampsia mixture + carbamazepine
Control group:Placebo + carbamazepine
Sponsors
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.The informed consent is signed; 2.Male or female aged 40 to 85 years; 3.Western clinical diagnosis conforms to the diagnostic criteria of epilepsy with cognitive impairment; MOCA [7] <26 points or MMSE [8] < 27 points; 4.Traditional Chinese medicine syndrome differentiation and stasis syndrome, phlegm syndrome, phlegm and stasis syndrome; 5.Have good compliance and informed consent; 6.Patients who meet the diagnosis.
Exclusion criteria
Exclusion criteria: 1.Breast-feeding or pregnant women; 2.Complicated with heart, brain, liver, kidney and hematopoietic system and other serious primary diseases; 3.Patients with severe intracranial infection or brain tumor; 4.Patients with serious mental diseases who cannot cooperate; patients with severe hearing loss; 5.Have recently undergone surgery or have serious injuries; 6.Patients with contraindications to the drug under study; 7.Patients who are in critical condition and find it difficult to accurately evaluate the effectiveness and safety of new drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Epilepsy frequency and clinical efficacy evaluation; | — |
Countries
China
Contacts
Public ContactYu Yangyang
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed