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Effect and mechanism of bifidobacterium bifidum CCFM1192 on respiratory allergy in infants: a randomized, double-blind, controlled trial.

Effect and mechanism of bifidobacterium bifidum CCFM1192 on respiratory allergy in infants: a randomized, double-blind, controlled trial.

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053121
Enrollment
Unknown
Registered
2021-11-12
Start date
2021-11-10
Completion date
Unknown
Last updated
2022-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma and allergic rhinitis

Interventions

Experimental group:Bifidobacterium infantile CFM1192

Sponsors

The People's Hospital of Tinghu, Yancheng City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1.Consistent with the diagnosis of respiratory allergy; 2.Aged 3 to 14 years, male or female; 3.Good compliance, able to comply with the requirements of clinical trials; 4.Before treatment, blood, urine and stool routine, liver and kidney function tests were within the normal range; 5.The patient was willing to sign the informed consent form and could be followed up.

Exclusion criteria

Exclusion criteria: 1.Known to be allergic or intolerant to any ingredient in the experimental probiotic product; 2.Patients who had received systemic glucocorticoid treatment within 1 week before the test, or patients with systemic treatment (immunosuppressant, cell growth inhibitor); 3.Immunosuppressive patients (such as lymphoma) or patients with a history of malignant diseases complicated with any disease that interferes with the evaluation of test results; 4.Pregnant or lactating women; 5.Frequently take probiotic products or eat yogurt and probiotic drinks for a long time in the near future (within 1 month); 6.Recent (within 1 month) or long-term use of antibiotics.

Design outcomes

Primary

MeasureTime frame
Base data;Bronchial asthma;Fecal flora;Allergic rhinitis;Immunoassay;Bacteria detection;

Countries

China

Contacts

Public ContactLu Wenwei

Jiangnan University

luwenwei@jiangnan.edu.cn+86 18762691080

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026