Healthy children and autistic children
Conditions
Interventions
Intervention group:External apply CureCode Double Barrier Cream
Non-treatment intervention group:None
Sponsors
The First Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
3 Years to 6 Years
Inclusion criteria
Inclusion criteria: Healthy children: 1.Healthy preschoolers aged 3 to 6 years; 2.No skin lesions on both forearms. Autistic children: 1.Patients with autism spectrum disorders diagnosed by child psychiatrists, developmental pediatricians, child psychotherapists or child therapists, and meeting the diagnostic criteria of DSM-5; 2.Diagnose was verified according to CARS-2; 3.Preschool children aged 3 to 6 years; 4.There were no significant changes in behavior or medical treatment in the past two months, and no changes were planned for the next two months of the study.
Exclusion criteria
Exclusion criteria: Healthy children: Diagnosed as atopic dermatitis (AD) or other skin diseases involving the whole body. Autistic children: 1.Diagnosed with other mental disorders, including attention deficit hyperactivity disorder (ADHD), compulsion, anxiety, depression, etc.; 2.Diagnosed with organic brain injury, epilepsy, or other neurological diseases; 3.Patients with skin lesions on both forearms, diagnosed as atopic dermatitis (AD), or allergic history to cosmetic ingredients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transepidermal water loss, TEWL;Stratum corneum hydration, SCH;Skin surface pH; | — |
Secondary
| Measure | Time frame |
|---|---|
| Childhood Autism Rating Scale (CARS) Score;Autism Treatment Evaluation Checklist (ATEC) Score;Autism Behavior Checklist (ABC) Score;Social Responsiveness Scale (SRS) Score;Repetitive Behavior Scale-Revised (RBS-R) Score; | — |
Countries
China
Contacts
Public ContactZhang Guoqiang
The First Hospital of Hebei Medical University
Outcome results
None listed