Degenerate meniscus lesions
Conditions
Interventions
control group:placebo
Sponsors
The First Affiliated Hospital of Southern University of Science and Technology (Shenzhen People's Hospital)
Eligibility
Sex/Gender
All
Age
40 Years to 90 Years
Inclusion criteria
Inclusion criteria: The patient, aged 40 to 90 years, was clinically diagnosed with osteoporosis, lumbar spondylolisthesis, low back pain or numbness (MRI confirmed lumbar disc herniation and signs of nerve compression).
Exclusion criteria
Exclusion criteria: 1. Previous cancer and received corticosteroid therapy; 2. Atrophy of cauda equina, progressive neurological deficit, malignant tumor; 3. Lumbar scoliosis and kyphosis greater than 15 degrees, previous back surgery and other established contraindications for elective surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| osteocalcin in the N terminal molecular fragment;n-terminal propeptide P1NP of procollagen type 1;c-terminal crosslinking type 1 collagen terminal peptide CTx;serum total calcium;parathyroid hormone;total phosphorus;albumin;bone density;hip bone mineral density;symptom duration;Numeric Rating Scale for Pain;Visual Analogue Scale pain questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| Roland Morris (RQD) disability function Questionnaire;Osteoporosis QUALEFO-31 questionnaire;EQ-5D quality of life questionnaire; | — |
Countries
China
Contacts
Public ContactWang Hongyu
The First Affiliated Hospital of Southern University of Science and Technology (Shenzhen People's Hospital)
Outcome results
None listed