Effects of different muscle relaxation depths on postoperative residual neuromuscular block and clinical recovery in patients undergoing ambulatory arthroscopic surgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100053039

Enrollment

Unknown

Registered

2021-11-10

Start date

2021-12-01

Completion date

Unknown

Last updated

2022-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee joint disease

Interventions

Group S (shallow block group):Low dose rocuronium

Group M (moderate block group):Continuous infusion of rocuronium

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Select patients undergoing general anesthesia for unilateral arthroscopic surgery, ASA I-II grades; 2. Aged 18-65 years; 3. BMI 18-30 kg/m^2; 4. The operation time is less than or equal to 3h; 5. Communication is normal; 6. Voluntarily test and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Neuromuscular disorders: myasthenia gravis, myasthenic syndrome, etc.; 2. (Family) history of malignant hyperthermia, allergy to the drugs used; 3. Severe liver and kidney insufficiency; 4. History of gastroesophageal reflux, etc.; 5. Possible difficult airway; 6. Preoperative life can not take care of themselves and so on.

Design outcomes

Primary

Measure	Time frame
incidence of postoperative residual neuromuscular block;nTOFr during extubation;	—

Secondary

Measure	Time frame
extubation time;Assessment of muscle strength recovery 15 min after extubation;15-item Quality of Recovery, QoR-15;PACU residence time;	—

Countries

China

Contacts

Public ContactSun Xuemei

The First Affiliated Hospital of Anhui Medical University

18715519369@126.com+86 18715519369

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026