Effects of femoral nerve combined with sciatic nerve block on oxidative stress and ischemia-reperfusion injury in children undergoing lower limb surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100053031

Enrollment

Unknown

Registered

2021-11-10

Start date

2021-11-10

Completion date

Unknown

Last updated

2022-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower limb surgery in children

Interventions

group C:general anesthesia

group T:General anesthesia combined with nerve block

Eligibility

Sex/Gender

All

Age

6 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1.ASA class I-II; 2.BMI < 25kg/m^2; 3.The children who underwent knee arthroscopy were given informed consent by their families.

Exclusion criteria

Exclusion criteria: 1. Children with previous hip and lower limb surgery; 2. Children with fractures and tumor-related diseases; 3. Those with metabolic diseases such as diabetes; 4. Those with infectious diseases or long-term use of hormones; 5. Those who are using cholinergic and adrenergic drugs; 6. Patients with severe anemia and coagulation disorders; 7. There is a history of local anesthetic or related drug allergy; children who cannot complete pain assessment.

Design outcomes

Primary

Measure	Time frame
Face Legs Activity Cry Consolability score;	—

Countries

China

Contacts

Public ContactXia Qin

Xinhua Hospital Affiliated to Medical College of Shanghai Jiaotong University

Xq_1203@126.com+86 15505158136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026