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Clinical trial study of intravenous lidocaine in the treatment of perioperative respiratory complications in patients undergoing tonsillectomy and/or adenoidectomy

Clinical trial study of intravenous lidocaine in the treatment of perioperative respiratory complications in patients undergoing tonsillectomy and/or adenoidectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100053006
Enrollment
Unknown
Registered
2021-11-08
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory system complications in patients undergoing tonsillectomy and/or adenoidectomy

Interventions

Group A:lidocaine 0mg/kg
Group B:lidocaine 1mg/kg
Group C:lidocaine 2mg/kg
Group D:lidocaine 1.5mg/kg

Sponsors

Yichang Central People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged >= 3 years; 2. ASA classification I~II; 3. The estimated anesthesia operation time is <= 120min; 4. The patient himself or the legal client signs the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Body mass index (BMI) = 23.9 kg/m^2; weight upper limit of normal); liver function impairment 9. (ALT and or AST >1.5 times the upper limit of normal value); 10. Patients with a history of severe head trauma and intracranial hypertension within 6 months; 11. Patients with mental or neurological diseases, or unable to express their wishes correctly; 12 Patients with a history of taking long-term sedative and analgesic drugs or monoamine oxidase inhibitors; 13. The estimated blood loss during surgery is greater than 100ml; 14. Those who have participated in other drug clinical trials within the past month; 15. Patients who cannot be scored by ASA or FLACC due to various reasons; 16. Accompanied by other conditions, the investigator believes that the patients are not suitable for selection. 17. Abnormal breath holding test. 18. Did not quit smoking in the recent half a month. 19. Patients with hypertension or with arrhythmia.

Design outcomes

Primary

MeasureTime frame
Sufentanil induced cough times; extubation coughing times;Hemodynamic parameters within five minutes after induction of intubation;Hemodynamic indexes within five minutes after extubation;Sore throat score after surgery;

Secondary

MeasureTime frame
Extubation time;Number of cases of additional drug use;Vas pain score within 24 hours;Number of cases of postoperative nausea and vomiting;

Countries

China

Contacts

Public ContactGong Yuan

Yichang Central People's Hospital

gy-yc@163.com+86 13986746821

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026