Skip to content

Comparative dose-response study of hyperbaric ropivacaine for spinal anesthesia for cesarean delivery in preterm versus term pregnancies

Comparative dose-response study of hyperbaric ropivacaine for spinal anesthesia for cesarean delivery in preterm versus term pregnancies

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052991
Enrollment
Unknown
Registered
2021-11-07
Start date
2021-11-11
Completion date
Unknown
Last updated
2022-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia for cesarean delivery

Interventions

Group EMP-1 :Ropivacaine10mg
Group EMP-2:Ropivacaine12mg
Group EMP-3:Ropivacaine14mg
Group EMP-4:Ropivacaine16mg
Group EMP-5:Ropivacaine18mg
Group LP-1 :Ropivacaine10mg
Group LP-2:Ropivacaine12mg
Group LP-3: Ropivacaine14mg
Group LP-4: Ropivacaine16mg
Group LP-5: Ropivacaine18mg
Group T-1 :Ropivacaine10mg
Group T-2: Ropivacaine12mg
Group T-3:Ropivacaine14mg
Group T-4:Ropivacaine16mg
Group T-5: Ropivacaine18mg

Sponsors

Zhejiang Xiaoshan Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Maternal age between 18 and 40 years old; 2. ASA Level 2; 3. Height >= 150 cm, weight <= 100 kg.

Exclusion criteria

Exclusion criteria: 1. Intraspinal anesthesia is contraindicated; 2. Those who are allergic to amide local anesthetics; 3. Combined with gestational hypertension or preeclampsia; 4. Placenta previa; 5. Premature rupture of membranes; 6. The labor process enters an active period; 7. Multiple pregnancy; 8. Those who refuse to sign the informed consent; 9. Other circumstances.

Design outcomes

Primary

MeasureTime frame
Successful rate of combined spinal-epidural anesthesia;Sensory plane block;motor block;Pain score;

Secondary

MeasureTime frame
General maternal information;Maternal vital signs;Adverse effects;Neonatal outcome;

Countries

China

Contacts

Public ContactMei Zhong

Zhejiang Xiaoshan Hospital

meizhong@zju.edu.cn+86 18969979723

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026