Pancreatic ductal adenocarcinoma
Conditions
Interventions
Pancreatic cancer group:Nil
Pancreatic intraepithelial neoplasia group:Nil
Control group:Nil
Sponsors
Drum Tower Hospital Affiliated to Medical School of Nanjing University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Pancreatic cancer group (30 cases): 18-80-year-old pancreatic cancer patients who did not undergo radiotherapy and chemotherapy, underwent ERCP to reduce jaundice due to obstructive jaundice caused by pancreatic cancer, and intubated the pancreatic duct several times during the operation. Post-pancreatitis, place the nasopancreatic duct and collect pancreatic juice at the same time; 2. Pancreatic precancerous lesions (PanIN) group (30 cases): patients aged 18-80 who underwent ERCP due to pancreatic duct stenosis, underwent pancreatic duct brushing or direct pancreatic ductoscopy to take biopsy confirmed PanIN, placed the nasopancreatic duct, and collected them at the same time. pancreatic juice; 3. Control group (30 cases): 18-80 years old, ERCP stone extraction was performed due to common bile duct stones, and the pancreatic duct was intubated several times during the operation. In order to prevent postoperative pancreatitis, the nasopancreatic duct was placed and the pancreatic juice was collected at the same time.
Exclusion criteria
Exclusion criteria: 1. History of other malignant tumors; 2. Receive chemotherapy within 30 days before enrollment; 3. Pancreatic surgery; 4. Abnormal biliopancreatic confluence; 5. Unable to cooperate with relevant serological, imaging examinations or surgery; 6. Patients who do not agree or are unable to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exosome form pancreatic Juice;CTC from pancreatic juice; | — |
Countries
China
Contacts
Public ContactShen Shanshan
Drum Tower Hospital Affiliated to Medical School of Nanjing University
Outcome results
None listed