Effect of oxycodone-esmketamine PCIA combined with paravertebral nerve block on postoperative analgesia in patients with thoracoscopic lung cancer

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052980

Enrollment

Unknown

Registered

2021-11-07

Start date

2021-11-06

Completion date

Unknown

Last updated

2022-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesiology

Interventions

Group SE:Sufentanil-esmketamine

Group S:Sufentanil

Group Q:Oxycodone

Eligibility

Sex/Gender

All

Age

45 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 45-75 years; American Society of Anesthesiologists (ASA) grade I or III; 2. The anesthesia plan adopts general anesthesia combined with paravertebral nerve block.

Exclusion criteria

Exclusion criteria: 1. Chronic renal failure (glomerular filtration rate 30 kg.m^2); 3. Hypersensitivity to the drugs used in the study.

Design outcomes

Primary

Measure	Time frame
Opioid consumption 72 hours after operation;	—

Secondary

Measure	Time frame
Intraoperative drug consumption and hemodynamics;PACU residence time, patient and surgeon satisfaction;Postoperative pain score, comfort score and functional activity score;Effective pressing times and proportion of postoperative analgesic pump;	—

Countries

China

Contacts

Public ContactRen Chunguang

Liaocheng People's Hospital

weiyichunguang@163.com+86 13561239696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026