Diabetes cardiovascular autonomic neuropathy
Conditions
Interventions
case series:No
Sponsors
Ningbo Huamei Hospital,University of Chinese Academy of Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Inpatients from Department of Endocrinology and Department of Cardiology, Ningbo Huamei Hospital, University of Chinese Academy of Sciences; 2. Diagnosis of type 2 diabetes:Three more symptoms and one less symptom + fasting blood glucose >= 7.0 or random blood glucose >= 11.1 or 75g OGTT 2h >= 11.1 mmol/L (OGTT is performed when fasting blood glucose >= 6.1 or random blood glucose >= 7.8); If there are no symptoms of three more and one less, it needs to be re-tested for confirmation on another day; Excluding stress, it can be combined with glycosylated hemoglobin >= 6.5%; 3. Or diagnosed with prediabetes: fasting blood glucose >= 6.1mmol/L, = 7.8, <11.1mmol/L; 4. Understand and sign the informed consent form before proceeding with any steps related to this study; 5. Agree not to participate in other studies, and try not to accept other drugs or clinical interventions that affect cardiovascular autonomic function during the study period, and make records when necessary.
Exclusion criteria
Exclusion criteria: 1. Cardiovascular organic diseases: dilated cardiomyopathy, rheumatic heart disease, pulmonary hypertension, pulmonary heart disease, restrictive heart disease and other definite cardiovascular structural and functional abnormalities, but atherosclerotic cardiovascular disease (ASCVD) not excluded; 2. Other diseases that may affect the cardiovascular autonomic nervous system: pheochromocytoma, hyperthyroidism, hypothyroidism, mental diseases, etc.; 3. Pregnant women, lactating women or those who use estrogen contraception, who do not use effective contraception, and who have the intention of becoming pregnant within 1 year; 4. Severe liver and kidney disease (GFR < 30 mL/min/1.73m2) and other serious diseases that need to be excluded by the investigator's judgment; 5. Those with alcoholism or intravenous drug addiction within 3 months; 6. Those who are positive for infectious diseases, including HIV, HBV, HCV, and syphilis; 7. Patients with a history of mental illness; 8. Those who have participated in other clinical investigators in the past 3 months and cannot comply with the research protocol; 9. Any other conditions that the investigator judges that the patient is not suitable for inclusion in the clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heart rate variability;blood pressure variability; | — |
Countries
China
Contacts
Public ContactYe Honghua
Ningbo Huamei Hospital, University of Chinese Academy of Sciences
Outcome results
None listed