Influence of respiratory rate on the central venous-arterial carbon dioxide partial pressure difference as a resuscitation index during the early treatment of septic shock

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052958

Enrollment

Unknown

Registered

2021-11-06

Start date

2021-12-01

Completion date

Unknown

Last updated

2022-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic shock

Interventions

Low frequency ventilation group:Low respiratory rate mechanical ventilation

High frequency ventilation group:High respiratory rate mechanical ventilation

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: The patients who needed mechanical ventilation and were diagnosed as sepsis or septic shock (sepsis 3.0 standard) in the emergency department from November 2021 to June 2022 were collected. The hemodynamic changes were monitored by pulse indicator Continuous Cardiac Output (PiCCO) and the treatments were guided.

Exclusion criteria

Exclusion criteria: Pregnancy, age less than 18 years patients with liver failure and irreversible underlying disease such as end-stage neoplasm.

Design outcomes

Primary

Measure	Time frame
Central venous-arterial carbon dioxide partial pressure difference;	—

Countries

China

Contacts

Public ContactXu Xin

Hebei General Hospital

xydh1980@163.com+86 13931846943

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026