Knee osteoarthritis
Conditions
Interventions
Sinomenine daily treatment group:During the course of treatment, sinomenine injection was injected into the articular cavity every day.
Sinomenine treatment group every other day.:Sinomenine injection was injected into articular cavity every other day during the course of treatment.
Sponsors
The Second Affiliated Hospital of Shaanxi University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Select KellgrenLawrence radiology standard I-III patients with stable disease, no contraindications for intra-articular injection therapy, and only single-joint treatment.
Exclusion criteria
Exclusion criteria: 1. Meet the diagnostic criteria for osteoarthritis and have gout, Kashin-Beck disease, ankylosing spondylitis, rheumatoid arthritis and other metabolic osteoarthritis and rheumatic immune diseases; 2. Women who are breastfeeding pregnant or are about to become pregnant; take drugs that affect the observation of this trial, such as glucocorticoids, non-steroidal anti-inflammatory drugs, immunosuppressive drugs, etc. 1 week before enrollment, suffer from hypertension, coronary heart disease Stable, diabetic, abnormal blood sugar.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Curative effect index;Inflammatory markers; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reaction; | — |
Countries
China
Contacts
Public ContactKou Jiushe
The Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine
Outcome results
None listed