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Clinical trial of ultrasound-guided percutaneous intramyocardial septal radiofrequency ablation myocardium for hypertrophic cardiomyopathy

Clinical trial of ultrasound-guided percutaneous intramyocardial septal radiofrequency ablation myocardium for hypertrophic cardiomyopathy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052944
Enrollment
Unknown
Registered
2021-11-06
Start date
2021-11-15
Completion date
Unknown
Last updated
2022-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertrophic Cardiomyopathy

Interventions

PIMSRA group:percutaneous intramyocardial septal radiofrequency ablation

Sponsors

Department of Ultrasound, the Second Affiliated Hospital of Army Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years; 2. Obstructive hypertrophic cardiomyopathy (LVOTG>=50mmHg (at rest or after challenge)); 3. Obvious clinical symptoms, fatigue, shortness of breath, exertional angina pectoris, syncope, etc., which seriously affect the quality of life, insufficient drug treatment effect or intolerable drug side effects; 4. Be able to understand the purpose of the clinical trial, participate voluntarily and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Active infection needs to receive antibiotic treatment at the same time; 2. Combined with other heart diseases requiring surgical treatment; 3. Left ventricular ejection fraction 2.0mg/dL or 177µmol/l) or receiving dialysis treatment; 8. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
peak left ventricular outflow tract gradient;anterior interventricular septum thickness;posterior interventricular septum thickness;

Secondary

MeasureTime frame
Mitral regurgitation volume;

Countries

China

Contacts

Public ContactXia Hongmei

Department of Ultrasound, Second Affiliated Hospital of Army Military Medical University

xiahm985206@126.com+86 13228685206

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026