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Withdraw. Study on the correlation between circulating tumor cell (CTC) typing and VEGFR2 mRNA expression level and therapeutic effect of advanced hepatocellular carcinoma

Study on the correlation between circulating tumor cell (CTC) typing and VEGFR2 mRNA expression level and therapeutic effect of advanced hepatocellular carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100052918
Enrollment
Unknown
Registered
2021-11-06
Start date
2021-12-01
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma (HCC)

Interventions

Sponsors

Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 70, ECOG score 0-2; 2. All patients met the clinical diagnostic criteria for hepatocellular carcinoma in The Code for The Diagnosis and Treatment of Primary Liver Cancer 2018 Edition; 3. No gender limitation, willing to receive normative treatment; 4. All patients never had any other primary tumor; 5. All patients were tested for liver function, five items of HEPATITIS B, HBV DNA, anti-HCV, HCV RNA, AFP and other biochemical indicators. Imaging analysis included abdominal ultrasound, enhanced CT or MRI, etc. 6. All patients have clear clinical data (including tumor size, tumor number, vascular invasion, capsule integrity, distant metastasis, local invasion or satellite focus, tumor grade, B-ultrasound or CT results, etc.), which can be further confirmed by liver puncture and pathological examination if necessary; 7. Informed consent was voluntarily signed by all patients for peripheral blood collection or liver penetrating pathological biopsy and application of molecular targeted drugs.

Exclusion criteria

Exclusion criteria: 1 Combined with other malignant tumors (including those who have been cured); 2. Combined with severe neurological and psychiatric diseases; 3. Control unstable diabetes, hypertension, thyroid disease, etc.; 4. Patients deemed by the investigator to be unsuitable to participate in this study.

Design outcomes

Primary

MeasureTime frame
Time to progress;Overall survival;

Secondary

MeasureTime frame
circulating tumor cells;

Countries

China

Contacts

Public ContactDeng Ying

Sichuan Provincial People's Hospital

909690405@qq.com+86 18628109320

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026