Hepatocellular carcinoma (HCC)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 70, ECOG score 0-2; 2. All patients met the clinical diagnostic criteria for hepatocellular carcinoma in The Code for The Diagnosis and Treatment of Primary Liver Cancer 2018 Edition; 3. No gender limitation, willing to receive normative treatment; 4. All patients never had any other primary tumor; 5. All patients were tested for liver function, five items of HEPATITIS B, HBV DNA, anti-HCV, HCV RNA, AFP and other biochemical indicators. Imaging analysis included abdominal ultrasound, enhanced CT or MRI, etc. 6. All patients have clear clinical data (including tumor size, tumor number, vascular invasion, capsule integrity, distant metastasis, local invasion or satellite focus, tumor grade, B-ultrasound or CT results, etc.), which can be further confirmed by liver puncture and pathological examination if necessary; 7. Informed consent was voluntarily signed by all patients for peripheral blood collection or liver penetrating pathological biopsy and application of molecular targeted drugs.
Exclusion criteria
Exclusion criteria: 1 Combined with other malignant tumors (including those who have been cured); 2. Combined with severe neurological and psychiatric diseases; 3. Control unstable diabetes, hypertension, thyroid disease, etc.; 4. Patients deemed by the investigator to be unsuitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to progress;Overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| circulating tumor cells; | — |
Countries
China
Contacts
Sichuan Provincial People's Hospital