Acute Coronary Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. History of stale heart attack or coronary angiography confirmed at least one coronary artery stenosis >= 50%; 2. The patient was clinically asymptomaticstable angina pectoris or acute coronary syndrome over 1 month stable condition; 3. Aged 30-75 years; 4. Volunteer to participate in and cooperate with the study, sign the informed consent, complete the diagnosis information, and be able to determine the syndrome elements.
Exclusion criteria
Exclusion criteria: 1. Chest pain caused by myocarditis, cardiac neurosis, gastroesophageal reflux, cervical spondylosis, hyperthyroidism, intercostal neuralgia; 2. Patients with severe hypertension, severe arrhythmia, severe cardiopulmonary insufficiency, stroke, nephritis, renal failure, rheumatism, liver, kidney, hematopoietic system, endocrine system and other serious diseases and osteoarthropathy; 3. Patients with acute infection (within 4 weeks) and who are taking antibiotics; 4. Patients during pregnancy or lactation or with allergic constitution; 5. Previous history of mental illness, dementia, alcohol or drug dependence; 6. Taking anti-anxiety and depression drugs; 7. Patients with poor compliance, and unable to communicate normally.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Elements of TCM syndrome;Anxiety/depression state;Blood pressure;History of diabetes;Blood fat (total cholesterol, high-density lipoprotein, low density lipoprotein, triglyceride);Left ventricular hypertrophy;Smoking history;Fasting plasma glucose;New or recurrent ACS(Acute Coronary Syndrome);SEN(sensitivity), SPE(specificity), ACC(accuracy), AUC(area under curve) of ROC(receiver operating characteristic curve); | — |
Secondary
| Measure | Time frame |
|---|---|
| Myocardial enzyme (creatine kinase isoenzyme, creatine kinase, lactic dehydrogenase, aspartate transferase, a-hydroxybutyric dehydrogenase);Troponin;Myohemoglobin;HCY(homocysteine);Interleukin-6;Hypersensitive C-reactive protein; | — |
Countries
China
Contacts
Zhujiang Hospital of Southern Medical University