head-neck tumor
Conditions
Interventions
Group 1:EGCG
Group 2:Physiological saline
Sponsors
Shandong Cancer Hospital and Institute
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients with locally advanced nasopharyngeal carcinoma were diagnosed by pathology and received simultaneous radiotherapy and chemotherapy for the first time; 2. ECOG 0 or 1; 3. The estimated survival time is more than 6 months; 4. 18-70 years old; 5. Normal bone marrow reserve function; 6. Normal renal function; 7. Normal liver function; 8. The electrocardiogram is normal; 9. The subjects agreed and signed the informed consent form; 10. There is no obvious inflammation of mouth and throat before radiotherapy, dental caries should be repaired first, residual roots should be removed as appropriate, and radiotherapy will be carried out after recovery.
Exclusion criteria
Exclusion criteria: 1. Those who receive targeted therapy and other treatments at the same time; 2. Allergic to EGCG or tea; 3. Pregnant or lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The efficiency of EGCG; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in blood biochemical indicators;Safty; | — |
Countries
China
Contacts
Public ContactZhu Wanqi
Shandong Cancer Hospital and Institute
Outcome results
None listed