Pulmonary complications
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Elective esophageal cancer surgery under general anesthesia with endobronchial intubation; 2. Aged 18-80 years; 3. ASA I-III.
Exclusion criteria
Exclusion criteria: 1. Obese (BMI >= 28 kg/m^2); 2. Contraindications of epidural block; 3. Severe kidney disease (glomerular filtration rate < 50 mL /min); 4. Serious liver disease (Child - Pugh, grade B or C); 5. History of myocardial infarction, heart failure, and respiratory failure; 6. Obstructive sleep apnea hypopnea syndrome (OSAHS); 7. History of spontaneous pneumothorax; 8. Neuromuscular diseases; 9. Respiratory infection within 1 month; 10. Cognitive dysfunction; 11. Failure to obtain informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of pulmonary complications ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary ultrasound score ;Arterial partial pressure of oxygen;Incidence of re-intubation;Unplanned oxygen therapy;Length of stay and cost;Incidence of unplanned ICU stay and length of ICU stay;30-day readmission rate;Health-related quality of life score ;Fitness score;All-cause mortality; | — |
Countries
China
Contacts
Cancer Center of Sun Yat-Sen University