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Prediction of the efficacy of liquid biopsy in immunocheckpoint inhibition therapy for advanced esophageal cancer

Prediction of the efficacy of liquid biopsy in immunocheckpoint inhibition therapy for advanced esophageal cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052844
Enrollment
Unknown
Registered
2021-11-06
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-08-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Esophageal cancer group:Immunosuppressive therapy

Sponsors

Guang'an People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with stage III-IV esophageal cancer who are inoperable or unwilling to operate; 2. Aged 18 to 80 years, has not received other immune checkpoint inhibition treatment, and is willing to accept immune checkpoint inhibition treatment (consistent with immunosuppressant manufacturers). 3. Gender unlimited; can tolerate relevant treatment; 4. Voluntarily participate in the study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. The patient had multiple distant metastases and the expected survival time was less than 3 months; 2. Combined with other tumors; 3. Patients with other serious chronic diseases such as chronic obstructive pulmonary disease and coronary heart disease affect their survival; 4. Patients who cannot obtain enough blood samples (>= 12 ml); 5. There are anemia, fever, low self immunity, incomplete coagulation function and other conditions that are not suitable for blood drawing; 6. Patients with autoimmune diseases and blood system diseases.

Design outcomes

Primary

MeasureTime frame
PFS(progress-free survival);

Secondary

MeasureTime frame
mOS(medium overall survival);

Countries

China

Contacts

Public ContactLong Xiangyu

Guang'an People's Hospital

371256871@qq.com+86 13508289655

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026