Severe acute pancreatitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Comply with SAP diagnosis and treatment guidelines formulated by Chinese Medical Association; 2. SAP as the primary diagnosis; 3. Aged 18 to 80 years; 4. No routine treatment such as acid and enzyme inhibition rehydration was performed before admission.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women; 2. Those who used antibiotics, hormones and other treatments within 3 months before the onset of the disease; 3. Accompanied by severe heart, liver and kidney dysfunction, immune deficiency, malignant tumor and other diseases; 4. Recent history of major surgery, trauma and infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| General Information (gender, age, blood pressure, heart rate, respiratory rate, body temperature, state of consciousness, Acute Physiology and Chronic Health Evaluation II score, Glasgow Coma Scale);Coagulation indexs (PT, APTT, D-Dimer, FIB);Microcirculation indexs (procalcitonin, C-reactive protein, interleukin, tumor necrosis factor, hematocrit, platelet count, blood lactate level, mixed venous oxygen saturation, mean arterial pressure);Conventional bacterial culture; | — |
Countries
China
Contacts
Affiliated Hospital of Xuzhou Medical University