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Study on the effect mechanism of Tongtiaodaimai acupuncture in regulating white fat browning in patients with abdominal obesity based on exosomal miRNA

Study on the effect mechanism of Tongtiaodaimai acupuncture in regulating white fat browning in patients with abdominal obesity based on exosomal miRNA

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052799
Enrollment
Unknown
Registered
2021-11-05
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal Obesity

Interventions

Treatment group:Acupuncture with tongtiaodaimai combined with lifestyle adjustment intervention.
Control group:Lifestyle intervention
Healthy group:None

Sponsors

The Second Clinical Hospital of Beijing University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Men's waist circumference (WC) >= 90cm, women's WC >= 80cm; 2. Aged between 18-55 years; 3. Patients who signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with secondary obesity caused by drugs, surgery, endocrine and other factors; 2. Patients who are taking birth control pills, diet pills, diet tea, diet nutrition meals, etc. for a long time; 3. Patients with cardiovascular, liver, kidney, brain and other primary diseases; 4. Patients with severe mental disorders; 5. Pregnant and lactating patients; 6. Patients who have participated in other treatments or studies in the past month.

Design outcomes

Primary

MeasureTime frame
Parameters of body fat;Plasma exosome miRNA ;Inflammatory factor;Browning gene;

Secondary

MeasureTime frame
Four items of blood lipid;Short-Term Nutrition Assessment Questionnaire (SNAQ);Weight on Quality of Life Scale Lite (IWQOL-Lite);

Countries

China

Contacts

Public ContactHu Hui
dfzhenjiu@126.com+86 13901156697

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026