A randomized, crossover, controlled clinical trial of intermittent hypoxia combined with transcutaneous electrical stimulation of the genioglossus in the treatment of obstructive sleep apnea

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052792

Enrollment

Unknown

Registered

2021-11-05

Start date

2021-12-01

Completion date

Unknown

Last updated

2022-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep apnea hypopnea syndrome

Interventions

Experimental group:Stimulation in different ways

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Normal subjects; 2. Patients with simple snoring; 3. Patients with obstructive sleep apnea of different severity.

Exclusion criteria

Exclusion criteria: 1. Those who do not sign the written informed consent; 2. Implanted cardiac pacing device; 3. Have arrhythmia, especially those who have not received treatment; 4. Those with impaired heart, liver, kidney and respiratory functions; 5. Patients with other chronic diseases such as tumors; 6. Those who lack the ability to act autonomously.

Design outcomes

Primary

Measure	Time frame
Apnea hyponea index;	—

Secondary

Measure	Time frame
Snoring index;Oxygen desaturation index;Adverse reaction;Tolerance;Sleepiness Scale Score;	—

Countries

China

Contacts

Public ContactHu Ke

Renmin Hospital of Wuhan University

huke-rmhospital@163.com+86 18971035988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026