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Effect of transcranial alternating current stimulation on cerebral cortical plasticity in healthy subjects

Effect of transcranial alternating current stimulation on cerebral cortical plasticity in healthy subjects

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052781
Enrollment
Unknown
Registered
2021-11-05
Start date
2021-11-05
Completion date
Unknown
Last updated
2022-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group P3:The main electrode is placed at P3
Group F3:The main electrode is placed in F3

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-35 years, gender is not limited; 2. No cognitive impairment measured by Mini Mental State Scale (MMSE) and Montreal Cognitive Assessment (MoCA); 3. GDS self-rating depression scale evaluation without depression; 4. Functional activity questionnaire (FAQ), BADL daily living ability scale (barthel index) showed normal activity; 5. Agree to participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Local skin infections, ulcers, scars or those who are overly sensitive to electrical stimulation; 2. Severe bleeding disorders and coagulation disorders; 3. History of epilepsy or seizures; first-degree relatives with history of epilepsy; 4. Metal implants on the body or head above the chest (except for stomatology), implanted with cardiac pacemaker defibrillators, cochlear implants, and drug pumps; 5. Unexplained recurrent headaches that are ineffective for drug treatment or taking tricyclic antidepressants, neuroleptics and other drugs that lower the seizure threshold; 6. Skull fracture and/or severe head injury; history of head and/or brain surgery; 7. Other diseases or medical history affecting cognitive function; 8. Those with severe visual or hearing impairment who cannot cooperate with the assessment; 9. Those with a history of smoking and alcoholism; 10. Pregnant or lactating patients.

Design outcomes

Primary

MeasureTime frame
Evaluation indicators related to transcranial magnetic stimulation (TMS);

Secondary

MeasureTime frame
Nonlinear dynamics analysis of EEG;

Countries

China

Contacts

Public ContactShan Chunlei
13045678102@163.com+86 13045678102

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026