auditory hallucinations in schizophrenia
Conditions
Interventions
Experimental group:continuous theta burst stimulation, cTBS
Control group:sham continuous theta burst stimulation
Sponsors
Ningbo Kangning Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Patients with schizophrenia (SZ) should be evaluated by clinical psychiatrists and meet the diagnostic criteria of ICD-10 (ICD); 2. Aged 18-50 years, currently receiving two or more antipsychotic drugs and the symptoms of auditory hallucinations persist; 3. The frequency of occurrence is more than 5 times a day; 4. There is no metal in the brain, no history of epilepsy in the past, and can cooperate with various experimental examinations; 5. Signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. History of brain trauma or head surgery; 2. For those with a pacemaker installed, the subject wears an in-ear hearing aid; 3. Combined with a history of other mental illnesses, such as depression, autism, developmental delay and a history of past drug abuse, recent suicidal tendencies, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive and negative symptom scale;Auditory hallucination scale;Brain evoked and event-related potentials;Functional near-infrared spectroscopy ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effect scale;Repetitive neuropsychological state test; | — |
Countries
China
Contacts
Public ContactLiu Xiaoli
Ningbo Kangning Hospital
Outcome results
None listed