Senile knee osteoarthritis
Conditions
Interventions
Control group a:Platelet-rich injection therapy
Control group b:Simple myofascial manipulation therapy
Experimental group:Platelet-rich plasma injection combined with myofascial manipulation therapy
Sponsors
The Fifth Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for knee osteoarthritis (KOA) in the Chinese Medical Association Orthopaedic Branch Osteoarthritis Diagnosis and Treatment Guidelines (2007 Edition); 2. Aged 50-75 years; 3. X-ray KellgrenLawrence (K-L) grades are in grades I-III; 4. Able to walk at least 10m without any assistive devices; 5. Voluntarily participate and cooperate to complete the research and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with advanced osteoarthritis with severe knee deformity; 2. Patients treated with cortisol hormones and analgesics in the past 1 month; 3. Patients who have undergone lower extremity surgery in the past 6 months; 4. Combined with diabetes, mental illness, severe immunosuppressive disease, blood disease (coagulation disorder), infectious disease, severe heart disease and liver and kidney insufficiency, patients with rheumatoid arthritis, rheumatoid immune arthritis, gout and Kashin-Beck disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Baseline information collection;Visual analogue scale scoring;Osteoarthritis index;Joint range of motion;Foot pressure analysis;Infrared thermal imaging;Muscle and bone ultrasound; | — |
Countries
China
Contacts
Public ContactYan Zheng
The Fifth Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed