Postoperative Neurocognitive Disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with colorectal tumors who are scheduled to undergo laparotomy; 2. According to the American Society of Anesthesiologists (ASA) classification, it is classified as I-III; 3. With the consent of the hospital ethics committee, the patients participated voluntarily and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Suffering from multiple sclerosis; 2. Suffering from various autoimmune diseases; 3. Suffering from diabetes; 4. Current infection (determined by clinical status, CRP and white blood cell count); 5. Severe visual or hearing impairment and MMSE score below 18; 6. History of alcohol or drug dependence, or taking psychotropic substances.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Soluble vascular cell adhesion molecule 1;Simple Mental State Examination Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;Body mass index;American Society of Anesthesiologists (ASA) Classification;Anesthesia and operation time;Intraoperatve blood loss;Intraoperative urinary volume;Intraoperative infusion volume;Intraoperative blood transfusion volume;Medications in operation; | — |
Countries
China
Contacts
The Fourth Affiliated Hospital of Harbin Medical University