depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for patients with depression: (1) Age: 15-34 years old; (2) Nationality: Han nationality; (3) Handy: right-handed; (4) Diagnostic criteria: meet the diagnosis of depression in DSM-V; (5) Drug use: currently using depression-related drugs; (6) 24-item Hamilton Depression Scale score greater than or equal to 12; (7) The single THINC-it test score is lower than the average of normal people; (8) Patients or their legal guardians agree to participate in this research and sign the informed consent. 2. Inclusion criteria for healthy volunteers: (1) Age: 15-34 years old; (2) Nationality: Han nationality; (3) Handy: right-handed; (4) Diagnostic criteria: not in line with the diagnosis of mental disorders in the Diagnostic and Statistical Manual of Mental Disorders (DSM-V); (5) Drug use: never used any antipsychotics, antidepressants, benzodiazepines or other drugs that can affect the central nervous system; (6) Subjects or their legal guardian agree to participate in this research and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for patients with depression: (1) Those who suffer from color blindness, color weakness, deafness, stuttering, etc.; (2) Be pregnant within one year; (3) Those with organic encephalopathy or nervous system disease; (4) Patients with high-risk diseases such as high blood pressure and heart disease; (5) Cardiopulmonary function test results are very poor or very poor; (6) Patients with a suicide plan or a history of attempted suicide; (7) Those who do moderate-intensity exercise for more than 100 minutes per week. 2. Exclusion criteria for healthy volunteers: (1) Those who suffer from color blindness, color weakness, deafness, stuttering, etc.; (2) Be pregnant within one year; (3) Those with organic encephalopathy or nervous system disease; (4) Subjects with high-risk diseases such as high blood pressure and heart disease; (5) Cardiopulmonary function test results are very poor or very poor; (6) Moderate-intensity exercise for more than 100 minutes per week.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index;Hamilton Depression Scale;Personal and Social Performance Scale;General Self-Efficacy Scale;The UCLA Loneliness Scale;Heart rate;The Borg Rating of Perceived Exertion Scale; | — |
Countries
China