Effects of surgery and prolonged sevoflurane anesthesia on markers of peripheral blood inflammation and nerve injury in children

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100052701

Enrollment

Unknown

Registered

2021-11-03

Start date

2021-11-16

Completion date

Unknown

Last updated

2022-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatobiliary disease

Interventions

Children's long-term general anesthesia group:None

Eligibility

Sex/Gender

All

Age

1 Years to 10 Years

Inclusion criteria

Inclusion criteria: 1. The operation time for children is more than 5 hours; 2. Children aged 1-10 years; 3. Surgery for hepatobiliary diseases.

Exclusion criteria

Exclusion criteria: 1. Combined with other encephalopathy; 2. Brain damage caused by hypoxia was found during operation.

Design outcomes

Primary

Measure	Time frame
Blood markers of brain injury;	—

Secondary

Measure	Time frame
Inflammatory factor;	—

Countries

China

Contacts

Public ContactShe Yingjun

Guangzhou Women and Children's Medical Center

yjsheh@yeah.net+86 13826012672

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026