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Evaluation of analgesic effect of hydromorphine combined with ropivacaine for horizontal block of erector spinal muscle in breast cancer surgery

Evaluation of analgesic effect of ultrasound-guided horizontal block of erector spine muscle with hydromorphine combined with ropivacaine in modified radical mastectomy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052700
Enrollment
Unknown
Registered
2021-11-03
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia in patients undergoing breast cancer surgery

Interventions

Group 1:Hydromorphone + Ropivacaine
Group 3:None

Sponsors

Xing'an League People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients voluntarily participate in clinical research and sign informed consent; 2. ASA I~II grade; 3. Aged 18 to 75 years; 4. Body mass index 18~25kg/m2; 5. The estimated operation time is 2~4h.

Exclusion criteria

Exclusion criteria: 1. Complicated with severe cardiovascular disease; 2. History of severe liver and kidney disease; 3. Combined with severe endocrine system diseases; 4. Complicated with severe blood system diseases or abnormal coagulation function and long-term use of antiplatelet and antithrombotic drugs; 5. Have a history of allergy to the drugs required for this study; 6. Pregnant women; 7. Combined with central nervous system or peripheral nervous system diseases; 8. Complicated with mental illness or cognitive dysfunction and unable to cooperate in completing the evaluation of various indicators; 9. There are contraindications to erector spinae plane block; 10. There is a history of chronic pain and long-term use of analgesic or sedative drugs.

Design outcomes

Primary

MeasureTime frame
Interleukin-6;

Secondary

MeasureTime frame
Visual analogue score;Sufentanil dosage;Propofol dosage;Remifentanil dosage;Rocuronium dosage;Postoperative patient-controlled intravenous analgesia pump dosage;Nausea and vomiting;First exhaust time after operation;The first time to get out of bed after operation;Postoperative hospital stay;

Countries

China

Contacts

Public ContactCao Xue

Xing'an League People's Hospital

675225601@qq.com+86 15849810683

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026