traumatic brain injury patients with cognitive impairmen
Conditions
Interventions
grouptraumatic brain injury group:No
healthy control group:No
Sponsors
The Second Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Hospitalized patients with traumatic brain injury; 2. Course of disease >= 1 month and <= 12 months; 3. Stable condition and stable vital signs; 4. Aged 18 to 85 years; 5. Not taking or injecting drugs that affect cognitive function within 1 month before enrollment; 6. Specialist assessment suggests cognitive impairment; 7. Voluntary participation, informed consent signed by the patient himself or his immediate family.
Exclusion criteria
Exclusion criteria: 1. Unconscious and difficult to complete the experiment; 2. Combined with severe neurological diseases; 3. People with severe mental illness or other mental disorders; 4. Cognitive impairment caused by other types of diseases, such as stroke, dementia with Lewy bodies, Pick disease, AD and other cognitive impairment; 5. The investigator believes that there is any situation that may harm the subject or cause the subject to be unable to meet or perform the research requirements; 6. Those with severe vision and hearing impairments; 7. Intracranial implantation of metal and electronic equipment; after skull defect and metal skull repair; 8. Disabled for patients with implanted electronic devices (such as pacemaker carriers); 9. Participating in another clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting brain function connection;Verbal fluency test, VFT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in Montreal Cognitive Assessment Scale (MOCA) scores;mini-Mental Status examination;clinical dementia rating;Event related potential P300; | — |
Countries
China
Contacts
Public ContactZhang Qiaojun
The Second Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed