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Clinical screening of myocardial amyloidosis in the elderly

Clinical screening of myocardial amyloidosis in the elderly

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100052678
Enrollment
Unknown
Registered
2021-11-03
Start date
2021-12-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myocardial amyloidosis

Interventions

Case series:none

Sponsors

Huadong Hospital affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Echocardiography: diffuse left ventricular wall thickening (end-diastolic wall thickness >= 12 mm) and right ventricular free wall thickening (end-diastolic wall thickness >= 7 mm), left ventricular myocardium showing ground-glass background and granular echoes Enhancement, double atrial enlargement, E/A ratio > 2 or E/e' ratio > 15, pericardial effusion; 2. ECG manifestations: non-left ventricular high voltage manifestations; 3. NT-proBNP > 300ng/L; or BNP > 100pg/dl.

Exclusion criteria

Exclusion criteria: 1. Hypertrophic cardiomyopathy; 2. Dilated cardiomyopathy; 3. Severe hypertension that is difficult to control.

Design outcomes

Primary

MeasureTime frame
Myocardial ground glassy background and granular echo;Ventricular wall thickness;Hydropericardium;electrocardiogram;—

Countries

China

Contacts

Public ContactShi Kailei

Huadong Hospital affiliated to Fudan University

1879542@qq.com+86 18121228705

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026