Timing of GnRH antagonists in IVF/ICSI antagonist protocol: a randomized controlled study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052666

Enrollment

Unknown

Registered

2021-11-03

Start date

2021-11-01

Completion date

Unknown

Last updated

2022-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

Experimental group1:Add antagonist

Control group1:No antagonist added

Experimental group2:Flexible plan

Control Group2:Fixed plan

Eligibility

Sex/Gender

Female

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20 to 35 years; 2. BMI 18.5-28kg/m2; 3. Regular menstrual cycles (21-35 days); 4. The subject voluntarily signs the informed consent.

Exclusion criteria

Exclusion criteria: 1. The number of cycles of previous ART >= 2; 2. Recurrent spontaneous abortion; 3. Patients with low ovarian function presented at least one of the following: poor previous ovarian response (the number of oocyte by previous routine gonadotropin stimulation <= 3), bilateral ovarian AF< 5 or AMH < 1.1ng/ mL; 4. PCOS patients; 5. Uterine myoma, untreated endometrial polyps, intrauterine adhesions, uterine malformations, ASRM stage III-IV endometriosis, ovarian cysts or hydrosalpinx and other factors that may affect pregnancy.

Design outcomes

Primary

Measure	Time frame
clinical pregnancy rate;implantation rate;	—

Countries

China

Contacts

Public ContactLi Caihua

The First Affiliated Hospital of Anhui Medical University

845313846@qq.com+86 18326613091

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026