Clinical study on early prevention and treatment of knee osteoarthritis based on QCT detection of trabecular bone abnormality under tibial plateau

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052664

Enrollment

Unknown

Registered

2021-11-03

Start date

2022-01-01

Completion date

Unknown

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee ostroarthritis and osteoporosis

Interventions

Experimental group:bisphosphonate

Control Group:No

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged over 50 years; 2. Have the ability to move on their own; 3. Current or past symptoms of joint pain; 4. Live in Shanghai.

Exclusion criteria

Exclusion criteria: 1. Severe neurological, respiratory, cardiac, liver and renal system diseases or malignant tumors; 2. Joint diseases involved in rheumatic immune system diseases; 3. The knee joint on the injured side; 4. Knee varus deformity; 5. Secondary osteoporosis caused by various reasons; 6. Have a history of knee surgery.

Design outcomes

Primary

Measure	Time frame
Microstructure of trabecular bone under tibial plateau;	—

Secondary

Measure	Time frame
Bone Density;	—

Countries

China

Contacts

Public ContactChen Minmin

Huadong Hospital affiliated to Fudan University

cmm86916@163.com+86 18916914526

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026