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Comparison low-intensity single-wavelength red light and low-dose(0.01%) atropine eye-drops to reduce progression of myopia in Chinese children: a randomized clinical trial

Comparison low-intensity single-wavelength red light and low-dose(0.01%) atropine eye-drops to reduce progression of myopia in Chinese children: a randomized clinical trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052653
Enrollment
Unknown
Registered
2021-11-03
Start date
2021-11-13
Completion date
Unknown
Last updated
2022-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mopia

Interventions

Experimental group:Wear monofocal frame glasses and illuminate both eyes with low-intensity red light (650nm)
Control group:Wear monofocal frame glasses, and apply 0.01% atropine eye drops to both eyes

Sponsors

Chongqing People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Children aged 6-12; 2. -6.00D = 0.20 logMAR; 5.10mmHg<= intraocular pressure <= 21mmHg; 6. Agree to random grouping and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Allergy to atropine or cyclopentanone; 2. Any type of strabismus or abnormal visual function; 3. Serious eye or systemic diseases; 4. Have used other methods of controlling myopia such as atropine eye drops, orthokeratology lenses, and defocusing glasses; 5. Those with mental retardation and hyperactivity who cannot cooperate with treatment and follow-up.

Design outcomes

Primary

MeasureTime frame
the progress of spherical equivalent (SE);

Secondary

MeasureTime frame
the progress of axial length;Change of corneal curvature;Change of uncorrected visual acuity (UCVA);The progress of choroidal thickness;Change of choroidal vascularity index;Change of retinal vascular density;Change of area of foveal avascular zone;Change of height and weight;

Countries

China

Contacts

Public ContactYi Hong

Chongqing People's Hospital

yihongln@163.com+86 13908326187

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026